NHUNGAMIDZO
HSV ihamvuropu, DNA-ine hutachiona morphologically yakafanana neimwenhengo dzegenus Herpesviridae.Two antigenically distinct types areinozivikanwa, yakasarudzwa mhando 1 uye mhando 2.

HSV Type 1 uye 2 inowanzobatanidzwa muhutachiona hwepamusoro hwemukanwamhango, ganda, ziso uye genitalia, Utachiona hwepakati tsingasystem (meningoencephalitis) uye hutachiona hwakanyanya hwese mumwana achangozvarwayemurwere ane immunocompromised anoonekwa zvakare, kunyangwe zvisingawanzo.Mushure mekutapukira kwekutanga kwakagadziriswa, hutachiona hunogona kunge huripo mune yakadzikama fomu mukutyamatishu, kubva kwaanogona kubuda zvakare, mune mamwe mamiriro ezvinhu, kukonzera akudzoka kwezviratidzo.

The classical kliniki mharidzo yegenital herpes inotanga nekuparariraakawanda anorwadza macules nemapules, ayo anobva akura kuita masumbu akajeka,mvura-yakazadzwa vesicles uye pustules.Ma vesicles anoputika uye anoita maronda.Gandamaronda crust, nepo maronda ari pa mucous membranes anopora pasina kuputika.Invakadzi, maronda anoitika paintroitus, labia, perineum, kana perianal nzvimbo.Varumekazhinji kuita maronda pa penial shaft kana glans.Murwere anowanzokuranyoro inguinal adenopathy.Zvirwere zvePerianal zvinowanikwawo muMSM.Pharyngitis inogona kukura nekuratidzwa nemuromo.

Ongororo dzeSerology dzinoratidza kuti vanhu vane mamirioni makumi mashanu muUnited States vane nhengo dzakavandikaHSV chirwere.MuEurope, HSV-2 inowanikwa mu8-15% yehuwandu hwevanhu.InAfrica, huwandu hwehuwandu huri 40-50% muvane makore makumi maviri.HSV ndiyo inotungamirachikonzero chezvironda zvesikarudzi.HSV-2 hutachiona hunowedzera kaviri njodzi yekusangana pabondekuwanikwa kwehuman immunodeficiency virus (HIV) uye inowedzerakutapurirana.

Kusvika nguva pfupi yadarika, hutachiona hwekuparadzaniswa musero tsika uye kutsunga kwemhando yeHSVine fluorescent staining yave iri musimboti wekuongororwa kweherpes muvarwerekuratidza maronda enhengo dzakavandika.Kunze kwePCR bvunzo yeHSV DNAyakaratidzwa kuva yakanyanya kunzwisiswa kupfuura hutachiwana tsika uye ine chaiyo iyoinodarika 99.9%.Asi nzira idzi mukuita zvekiriniki parizvino dzishoma,nekuti mutengo webvunzo uye chinodiwa kune vane ruzivo, vakadzidziswatekinoroji vashandi kuita bvunzo kurambidza kushandiswa kwavo.

Kune zvakare inotengeswa ropa ongororo inoshandiswa kuona TypeYakananga HSV masoja ekudzivirira chirwere, asi aya ekuongorora serological haakwanise kuona yekutangahutachiwana saka vanogona kushandiswa chete kutonga kunze kwezvirwere zvinowanzoitika.Iyi novel antigen bvunzo inogona kusiyanisa dzimwe genital maronda zvirwere nesikarudziherpes, senge syphilis uye chancroid, kubatsira kukurumidza kuongororwa uye kurapwautachiona hweHSV.

PRINCIPLE
Iyo HSV antigen Rapid Test Device yakagadzirirwa kuona HSV antigenkuburikidza nekududzirwa kwekuona kwekukura kwemavara mumutsara wemukati.Themembrane yakanga isingafambiswi ne anti Herpes simplex virus monoclonal antibody pa
dunhu rebvunzo.Panguva yekuedzwa, muenzaniso unobvumirwa kuita nemavaramonoclonal anti-HSV antibody colored particals conjugates, iyo yaive yakashongedzwa pairimuenzaniso pad yebvunzo.Musanganiswa unobva wafamba pa membrane ne capillary
chiito, uye inopindirana nemareagents pane membrane.Kana paine HSV yakakwanamaantigen mumienzaniso, bhendi rine ruvara richaumbwa panzvimbo yekuyedza ye membrane.Kuvapo kwebhandi iri remavara kunoratidza mhedzisiro yakanaka, nepo kusavapo kwayo kunoratidza
mhedzisiro yakaipa.Kuonekwa kwebhandi remavara panzvimbo yekutonga inoshanda seProcedural control.Izvi zvinoratidza kuti vhoriyamu yakakodzera yemuenzaniso yakawedzerwauye membrane wicking yakaitika.