ZVIRI KUSHANDISA
The StrongStep^®HPV 16/18 Antigen Rapid Test Device inokurumidza kuona immunoassay yemhando yekufungidzira yemhando yeHPV 16/18 E6&E7 oncoproteins mune yevakadzi cervical swab specimens.Iyi kit inotarisirwa kushandiswa seyamuro mukuongororwa kweCervical Pre-cancer neCancer.

NHUNGAMIDZO
Munyika dzichiri kusimukira, gomarara remuromo wechibereko ndiro riri kukonzera ndufu dzine chekuita negomarara pakati pemadzimai nekuda kwekusaitwa kweongororo yekuongorora cervical pre-cancer negomarara.Muedzo wekutarisa wezvishandiso zvakaderera zvigadziriso zvinofanirwa kunge zviri nyore, nekukurumidza, uye zvinodhura.Sezvineiwo, bvunzo yakadai ingave inodzidzisa maererano neHPV oncogenic chiitiko.Kutaura kwezvose zviri zviviri HPV E6 uye E7 oncoprotein kwakakosha kuti cervical cell shanduko iitike.Mimwe mhedzisiro yetsvagiridzo yakaratidza kuwirirana kweE6 & E7 oncoprotein positivity pamwe nekuomarara kwecervical histopathology uye njodzi yekufambira mberi.Nekudaro, E6&E7 oncoprotein inovimbisa kuve yakakodzera biomarker yeHPV-mediated oncogenic chiitiko.

PRINCIPLE
The StrongStep^®HPV 16/18 Antigen Rapid Test Device yakagadzirirwa kuona HPV 16/18 E6&E7 Oncoproteins kuburikidza nekududzira kwekuona kwekukura kweruvara mumutsara wemukati.Iyo membrane yakanga isingafambiswi nemonoclonal anti-HPV 16/18 E6&E7 masoja ekudzivirira chirwere munzvimbo yekuyedza.Munguva yekuedzwa, mufananidzo unobvumirwa kuita neruvara rwemonoclonal anti-HPV 16/18 E6&E7 masoja ekudzivirira ekudzivirira eruvara rweparicals conjugates, ayo aive akavharirwa pasample pad yebvunzo.Iko kusanganiswa kunobva kwafamba pa membrane ne capillary action, uye kupindirana nema reagents pa membrane.Kana pakanga paine yakakwana HPV 16/18 E6&E7 oncoprotein mumienzaniso, bhendi reruvara richaumbwa munzvimbo yekuyedza ye membrane.Kuvapo kwebhandi iri remavara kunoratidza mhedzisiro yakanaka, nepo kusavapo kwayo kunoratidza mhedzisiro yakaipa.Kuonekwa kwebhandi remavara panzvimbo yekutonga inoshanda senzira yekutonga.Izvi zvinoratidza kuti vhoriyamu yakakodzera yemuenzaniso yakawedzerwa uye membrane wicking yakaitika.

SPECIMN KUCHENGA UYE KUCHENGETA
∎ Hunhu hwemuenzaniso wawanikwa hwakakosha zvakanyanya.Zvakadarocervical epithelial cell inofanira kuunganidzwa ne swab.Kune cervical specimens:
■ Shandisa chete Dacron kana Rayon yakapfava isina mbereko ine simbi dzepurasitiki.Ndizvokurudzira kushandisa swab inopihwa nemugadziri wekiti (Iyo swab iriisina mukiti ino, kune ruzivo rwekuodha, ndapota taura neiyokugadzira kana muparidzi wepanzvimbo, iyo catalogue nhamba ndeye 207000).Swabskubva kune vamwe vatengesi haisati yasimbiswa.Swabs nemazano ekotoni kanamatanda emapuranga haakurudzirwi.
∎ Usati watora sampuli, bvisa machuru akawandisa kubva pamuromo wechiberekone swab yakasiyana kana bhora rekotoni uye bvisa.Isa swab mucervix kusvikira mafiibha epasi chete abuda pachena.Shingairira zvakasimba swabkwe 15-20 seconds mune imwe nzira.Dhonza swab kunze zvakanaka!
■ Usaise swab mune chero mudziyo wekutakura une pakati kubva ipapokufambisa svikiro kunovhiringa kuongororwa uye kugona kwezvipenyu ndizvohazvidiwi pakuongorora.Isa swab kune yekubvisa chubhu, kana bvunzoinogona kumhanya nekukurumidza.Kana kukurumidza kuongororwa kusingakwanisi, murweresampuli dzinofanirwa kuiswa muchubhu yekutakura yakaoma yekuchengetedza kana kutakura.Theswabs dzinogona kuchengetwa kwemaawa makumi maviri nemana patembiricha yemumba (15-30°C) kana svondo rimwepa 4°C kana kusadarika mwedzi mitanhatu pa -20°C.Yese mienzaniso inofanira kubvumidzwakusvika kune tembiricha yekamuri ye15-30 ° C isati yaedzwa.